Position: Postdoctoral Fellow
Site: Princess Margaret Cancer Research Tower
Department: Experimental Therapeutics
Reports to: Principle Investigator
Hours: 37.5 hours per week
Status: Temporary full time (1 year)
University Health Network (UHN) is looking for an experienced professional to fill the key role of Postdoctoral Fellow in our Experimental Therapeutics Department.
The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,600 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.
University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s seven research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.
We are seeking a recent PhD graduate or junior postdoctoral research fellow to join a lively research group to work in Experimental Therapeutics: www.vasconceloslab.com. The successful candidate will work closely with a Bioinformatician in the lab to study effective vascularization at the single cell level to enable high integration (retention) and improve cell-based vascularization using human pluripotent stem cell-derived endothelial cells. This project has high translational potential and applicability to several transplantation and disease models. The fellow will have access to in vitro, ex vivo, and in vivo research models, as well as various research techniques and advanced equipment. The successful candidate is expected to qualify for training grants and fellowships. As part of the training, the successful candidate will work as part of one or more projects and will acquire the research skills to be proficient in designing, managing, and performing experiments. You will also be expected to collect and analyse data and deliver experimental research reports when necessary; writing scientific manuscripts for publication in peer-reviewed journals, and present research data internally and externally. The fellow will also have the opportunity to write and be part in the preparation of external grant applications and fellowships.
Qualifications:
- PhD degree obtained within the last five (5) years or MD within the last ten (10) years in human genetics, molecular biology, or related field
- Experience in endothelial cell/vascular biology and be involved in a research project related to cell-based graft vascularization (Sun et al, Science Translational Medicine 2020; Aghazadeh et al, Cell Stem Cell 2021).
- Strong background in endothelial cell/vascular biology
- Experience in animal models, micro-dissection, cell culture techniques including primary cell isolation (such as FACs sorting and magnetic bead cell isolation) and culture, histology/immunohistochemistry is desirable
- Experience with cell differentiation from human embryonic of induced pluripotent stem cells is an asset.
- Work well both independently and as an effective member of a research team.
- Excellent written and verbal communication skills.
- Passionate about conducting scientific research.
- Demonstrates ethics and integrity.
Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.
More information and apply here.