Postdoctoral Research Fellowship: McEwen Stem Cell Institute

150 150 Office of Research Trainees

University Health Network (UHN) is looking for an experienced professional to fill the key role of Postdoctoral Fellow in the McEwen Stem Cell Institute.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,600 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s seven research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

The Protze lab studies human heart development with a specific focus on the cardiac conduction system that regulates the heartbeat. We are using pluripotent stem cells, single cell transcriptomics, and electrophysiology assays to study heart development and diseases in vitro. We also explore the application of the stem cell-derived conduction system cells as biological pacemakers in cell therapy approaches to treat heart rhythm disorders.

We seek a driven, motivated postdoctoral fellow for a recently funded Medicine by Design project that aims to combine synthetic biology approaches with stem cell research and cell therapies for the heart.

We offer a welcoming, dynamic, international team with cross-disciplinary expertise in pluripotent stem cell biology, developmental biology, cardiac electrophysiology and synthetic biology. The candidate will have the opportunity to work at the forefront of stem cell research with a focus towards clinical translation and to interact with a wide network of national and international collaborators as well as our industry partners.

• Received a PhD within 5 years or a MD within 10 years
• Experience in molecular biology techniques (RT-qPCR, cloning, western blot)
• Experience engineering human pluripotent stem cells using CRISPR-Cas system
• Experience culturing and differentiating human pluripotent stem cells
• Experience in flow cytometry
• Effective organizational, time management and prioritization skills
• Strong problem recognition and problem-solving skills
• Strong verbal and written communications skills
• Ability to effectively work as part of a team
The following would be considered as valuable assets:
• Background in cardiovascular research
• Experience in cardiac differentiations of human pluripotent stem cells
• Experience in immunohistochemistry
• Experience in patch clamp techniques
• Experience in optical mapping techniques

More info here.