Postdoctoral Research Fellowship: Princess Margaret Cancer Centre-Gaiti Lab

150 150 Office of Research Trainees

University Health Network (UHN) is looking for an experienced professional to fill the key role of Postdoctoral Fellow in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

Princess Margaret Cancer Centre (PM), a teaching hospital of the University of Toronto, has achieved an international reputation as a global leader in the fight against cancer and is considered one of the top comprehensive cancer treatment and research centres in the world. Princess Margaret Cancer Centre, together with its research institute, is a member of the University Health Network, which also includes the Toronto General Hospital, Toronto Western Hospital and Toronto Rehabilitation Institute. PM is the only facility in Canada devoted exclusively to cancer research, treatment, and education.

The Gaiti Lab at Princess Margaret Cancer Centre and University of Toronto is seeking post-doctoral scientists to study human somatic and cancer evolution using cutting edge molecular and computational approaches. Our work includes novel computational frameworks and single-cell multi-omics methodologies to decipher the interactions between genome, epigenome, and phenotype in human tissues. We implement a complementary approach of discovering cancer-specific signatures directly in patient samples through the powerful single-cell sequencing platforms and mechanistically defining these targets through model systems for translational impact. Our particular focus is on pioneering novel technologies and computational framework to study cancer evolution with single-cell multi-omics.


  • PhD degree obtained within the last five (5) years or MD within the last ten (10) years
  • MD or PhD in human genetics, molecular biology, or related field with expertise in any of the following: sequencing technologies, cellular/molecular biology, genomics technology development, murine modeling; or
  • PhD in computational biology, computer science, or a related field with expertise in analyzing next generation sequencing data, machine learning, biostatistics.
  • A publication record.
  • Excellent organizational and analytical skills, along with a high degree of independence and flexibility to thrive in a novel and rapidly evolving research environment.
  • Track record of teaching and mentoring students and technicians.
  • Ability to communicate and work effectively with a diverse team of clinicians and scientists, including post-docs, students, and technicians.

Career Development:

We value our trainee’s personal development and strive to unlock their full potential. Trainees are provided with ample opportunities for additional training in computational and cancer biology. Successful applicants are encouraged to attend scientific meetings and the lab will provide support for at least one scientific conference per year. While this position is not contingent upon securing additional funding, successful candidates will be supported and encouraged to apply for outside sources of funding. Candidates are welcomed to explore their own scientific interests into areas of research that fall within the general scope of the lab.

Interested applicants should submit their (1) CV with a list of publications; (2) a short summary of your present and future research interests; (3) a list of three references and their contact information.

Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

Closing Date: Until filled

More information and apply here.