Postdoctoral Research Fellowship: Princess Margaret Cancer Centre- Penn Lab

150 150 Office of Research Trainees

University Health Network (UHN) is looking for an experienced professional to fill the key role of Postdoctoral Fellow in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

The Penn lab is looking for an experienced and motivated scientist to spearhead projects focused on understanding the regulation, function and inhibition of the MYC oncoprotein. The applicant should have a strong scientific background, with knowledge of cancer biology, and expertise in a variety of biochemical and molecular biology techniques, including tissue culture, cloning techniques, genomics (e.g. chromatin immunoprecipitation, Cut’n’Run, RNA-seq), protein handling and bioactivity and functional assays.

The successful applicant will be expected to work both collaboratively and independently and will report directly to the PI.  The applicant will be expected to contribute to the scientific development of the project and be able to investigate, design, and conduct research assays related to both fundamental research and therapeutic development. Working in a fast-paced environment, the applicant will be a biologist with strong cell biology/molecular biology experience who can multi-task and enjoy contributing to research at many levels. The lab is situated in the Princess Margaret Cancer Research Tower within the Toronto discovery district.  Thus, the candidate will be part of a rich and vibrant scientific community.

 Qualifications

  • Recent completion of PhD (within five (5) years) in biochemistry, molecular biology, cell biology or related discipline
  • Three (3) years or more experience in genomics and/or proteomics
  • Experience in assay development, functional cell-based assays, cytotoxicity assays etc.
  • Experience working with tissue culture and lentivirus
  • Experience with DNA manipulation, i.e. PCR based mutagenesis, cloning etc.
  • Experience working with mice would be an asset
  • Experience in oncology/cancer malignancies would be an asset
  • Exceptional organizational skills and team-work ethic
  • Capable of multitasking with minimal direct supervision

Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter. You will also be required to complete some initial screening questions

Posted Date: December 9, 2021               Closing Date: Until Filled

More information and apply here.