Scientific Associate I at Princess Margaret Cancer Center

150 150 Office of Research Trainees

University Health Network (UHN) is looking for an experienced professional to fill the key role of Scientific Associate I at Princess Margaret Cancer Centre.


Job Posting # 909317

Position: Scientific Associate I 
Site: Princess Margaret Cancer Centre, MaRS Tower
Department: Research
Reports to: Principal Investigator
Pay Scale: $60,752 to $75,930 per annum (Commensurate with experience and consistent with UHN Compensation Policy)
Hours: 35 hours per week
Status: Permanent Full-time

University Health Network (UHN) is looking for an experienced professional to fill the key role of Scientific Associate I in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,600 physicians, 8,000+ students, and many volunteers.

The Princess Margaret Cancer Centre has 12 site groups and 26 specialty clinics, and almost 3,000 staff who see over 400,000 patient visits every year. Its 800,000 square feet house 130 inpatient beds, 373,000 square feet of research space and 17 radiation treatment machines, making it one of the largest comprehensive cancer treatment facilities in the world and the largest radiation treatment centre in Canada. Find out about our purpose, values and principles here.

The Scientific Associate I  will primarily be involved in laboratory studies of new cancer treatments with a high potential for translation to the clinic. This will require advanced knowledge of laboratory-based research methods, including but not limited to tissue culture, western blotting, chromatin immunoprecipitation and qRT-PCR. The Scientific Associate will be expected to work with a team to establish and perform a series of assays designed to evaluate the activity of novel, anti-cancer small molecule inhibitors. The Scientific Associate will ensuring accurate recording of experimental data, have excellent competency in written and verbal communications and be expected to assist with manuscripts and grant applications. The ability to work with people from different disciplines and with varying levels of scientific and technical expertise is required.


  • A PhD in the biological sciences
  • At a minimum, one (1) year of related biomedical laboratory research experience
  • Strong background and relevant experience in robust assay development and evaluating small molecule inhibitor activity
  • Excellence in 2D and 3D mammalian cell culture and bioassays (Western blotting, ChIP, qRT-PCR)
  • Knowledge in bioinformatics preferred
  • Excellent problem recognition and problem-solving
  • Excellent verbal and written communication skills
  • Excellent interpersonal skills
  • Excellent organizational and time management skills
  • Ability to set priorities and work independently with accuracy in a fast-paced multitasking environment
  • Strong proficiency with MS Office software, Word, Excel, Outlook, and PowerPoint

Key Duties:

  • Apply advanced scientific research knowledge to distinguish small molecule inhibitors that demonstrate target-engagement and anti-cancer activity
  • Ensure the smooth daily operation of the research team focused on distinguishing lead compounds
  • Oversee the implementation of new laboratory techniques and technical developments
  • Oversee other lab personnel
  • Train staff and students on established and new procedures
  • Perform data analysis and interpretation, which may involve biostatistical and bioinformatic approaches
  • Assist with the preparation of manuscripts and grant applications

Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter. You will also be required to complete some initial screening questions.

Posting Date: November 3, 2022                       Closing Date: December 3, 2022

For more information and to apply, see here.